Called Heart On My Sleeve, the track simulates the two stars trading verses about pop star and actress Selena Gomez, who previously dated The Weeknd.
BBC reports the creator, known as @ghostwriter, claims the song was created by software trained on the musician's voices.
"This is just the beginning," they wrote under the song's YouTube video.
"We really are in a new era," responded one listener in the comments. "Can't even tell what's legit or fake anymore."