Myles was ruled out of Game Two with a knee injury suffered during Manly's loss to Penrith at Brookvale Oval on Sunday afternoon.
"He had some scans earlier today and those scans showed some damage," Queensland coach Kevin Walters told QRL.com.au.
"Our doctor was of the belief that Nate won't be fit enough to take the field on Wednesday week, which is very sad news for Nate and the Queensland team. But it opens up an opportunity for Jacob to come in from the New Zealand team.
