Zhu Jianqiang, or "Strong-Willed Pig", died on Wednesday night of "old age and exhaustion", according to the museum in China's Sichuan province where the animal resided.
At the time of its rescue, it was seen as a symbol of hope and resilience.
Millions of people have taken to social media site Weibo to remember the pig and pay tribute to its long life.
The Sichuan Museum of Jianchuan said Zhu Jianqiang had died at the age of 14.
The 7.9 magnitude quake in Sichuan in 2008 left nearly 90,000 people dead or missing.
