In a series of tweets, Jack Dorsey said he had travelled to northern Myanmar last month for a meditation retreat.
"The people are full of joy and the food is amazing," he said, before encouraging his 4m followers to visit.
But some accused him of ignoring the plight of the Muslim Rohingya minority.
Last year, Myanmar's military launched a violent crackdown after Rohingya militants carried out attacks on several police posts.
