Well, not a whole lot, except for the fact that all three have made scene-stealing appearances on sitcoms!
That's right, E!'s tallying up the top nine sitcom guest stars from over the years and the picks will without a doubt surprise you.
Who could forget the moment Cher and Sean Hayes tried to out-attitude one another during an episode of Will & Grace? And how ridiculously amazing was it that none other than Mrs. Beckham herself was dubbed "perfect spice" on Ugly Betty?