More than a dozen players and staff, including Ledesma, tested positive for coronavirus over the last few weeks as the Pumas assembled to prepare for the tournament starting in November.
Ledesma, however, said almost all had been asymptomatic and the testing regime in place meant he was sure they would travel to Australia next month.
"We're testing every 72 hours," Ledesma told the Sydney Morning Herald.
"We'll be tested 72 hours before leaving, and once we get into Australia we'll be tested again.