The World Rugby funded tournament replaces the former Pacific Rugby Challenge and aims to boost the high-performance pathway for tier-two nations.
Samoa A have been drawn in Pool A, alongside the Argentina XV and USA Selects, with Fiji Warriors, Canada A and Uruguay A in Pool B.
Teams will play each side in their opposite pool once, with the placing determined on total points after the three rounds.
World Rugby Vice-Chairm Agustín Pichot said the tournament is part of the governing body's strategy to boost tier-two teams in a World Cup cycle.