The cash value option of the jackpot is $780.5m. The winner can choose to take the cash outright or be paid the full jackpot in instalments over 29 years.
The odds of winning the jackpot in Friday's draw were rather slim - one in 300 million.
The largest Mega Millions prize to date was $1.537bn in 2018.
It was won by a single ticket sold in South Carolina. The 2016 Powerball prize, however, remains the largest jackpot in US history - $1.586bn - shared by three winners.