At least 91 deaths, including children, were recorded by the Assistance Association for Political Prisoners (AAPP), a local monitoring group.
"They are killing us like birds or chickens, even in our homes," resident Thu Ya Zaw told Reuters news agency in the central town of Myingyan.
"We will keep protesting regardless."
The lethal crackdown came as protesters defied warnings and took to the streets on the annual Armed Forces Day.
US, UK and EU officials condemned the violence, with British Foreign Minister Dominic Raab calling it a "new low".