Lady Gaga, Paul McCartney and Billie Eilish were among more than 100 artists who performed songs from their living rooms, due to the coronavirus lockdown.
The Rolling Stones even managed to play together from four separate locations.
The eight-hour show also featured real-life stories from those on the front line of the fight against Covid-19.
The event raised almost $128m (£102m), with proceeds going towards vaccine development and local and regional charities, organisers Global Citizen said.
