A group of 27 have been selected for resettlement, along with 25 from Papua New Guinea's Manus Island, under Australia's refugee swap deal with the US.
The refugees hail from Bangladesh, Iran, Sri Lanka, Somalia and Myanmar, and are bound for US states such as Arizona, Texas, California and New York.
Ian Rintoul of the Refugee Action Coalition has spoken to the refugees on Nauru, they said they're happy to be finally leaving.
