Mother! suggests a sympathetic, if essentialist view of women and their role: giving birth, nurturing life. And in this case, supporting a celebrity author husband with writer's block. But Ball and Chain! might have been more appropriate.
The film is a devastating portrayal of male selfishness in which an artist behaves appallingly to his wife who spends much of the movie trying to get his attention. He acts out of neglect more than anything else, but this triggers consequences that are catastrophic for her.