Goodhue will start at second-five against the Rebels in Melbourne on Sunday evening.
Goodhue has been out of action for 12 months after suffering a serious knee injury playing against the Hurricanes in Wellington last April.
He ruptured his anterior cruciate ligament, he damaged his medial collateral ligament and posterior cruciate ligament attempting a tackle.
The Crusaders are now preparing for a four-match tour in Australia, starting with their Anzac weekend fixture against the Rebels, the last game in Super Rugby Pacific's 'Super Round'.