The grim milestone came on the same day as global coronavirus cases exceeded 50m.
The US has reported about a million cases in the past 10 days, the highest rate of infections since the nation reported its first novel coronavirus case in Washington state 293 days ago.
The country reported a record 131,420 Covid-19 cases on Saturday and has reported over 100,000 infections four times in the past seven days, according to a Reuters tally.