Hodge fractured his ankle in an innocuous training incident and he will not play against the All Blacks in Japan or fly to Europe for the remainder of the Spring Tour.
Wallabies coach Michael Cheika confirmed the centre would not take part in his team's four remaining matches this season on Sunday.
Cheika is left with limited options in trying to replace Hodge.
Samu Kerevi may have to be rushed into a Test rugby return having played his first minutes since the June Tests in the Byron Bay Sevens at the weekend.
