The movie actor announced that Cyberpunk 2077 is set to go on sale on 16 April 2020.
The future-set role-playing game is being developed by CD Projekt Red, the studio behind the Witcher series.
Reeves - who has starred in the Matrix trilogy amongst other sci-fi movies - will appear in the title.
His brief appearance at the Xbox event drew huge applause with one attendee shouting: "You're breathtaking."
"No, you're breathtaking," the actor ad-libbed in reply.