Carlton youngster Liam Stocker will miss the next month due to bone stress in his foot.
However, there is good news on the injury front for the Blues, with former captain Marc Murphy and key defender Liam Jones nearing recovering from respective setbacks.
Stocker, 19, missed last Saturday's upset victory over Brisbane due to the foot injury, having previously played in five successive games after making his senior debut last month.
The rebounding defender, who the Blues traded up to secure in last year's NAB AFL Draft, was averaging 13.6 disposals per game and had impressed the club with his kicking ability.
"He unfortunately has some low-grade bone stress in his foot," Carlton's high performance boss Andrew Russell told carltonfc.com.au on Tuesday.
"It's not uncommon for a young guy of his age. It will probably mean he will miss three or four games, but he should come back strong and be able to finish the season."
Murphy will undergo a fitness test later this week, having sustained fractured ribs earlier in the season, with the club hopeful the midfielder will be fit to play the Western Bulldogs.
Jones is also back in full training, though the club will take a cautious approach with his return from five weeks out due to a heavy concussion sustained against North Melbourne.
The Blues don't believe Jones will return until at least after the club's round 14 bye.