For the first time since Malaysia Airlines flight MH17 was shot down in July 2014, prosecutors have announced charges against suspects in the case.
Three Russians and a Ukrainian have been charged with bringing a missile into the area in eastern Ukraine and with murdering 298 passengers and crew.
The passenger flight was en route from Amsterdam to Kuala Lumpur when it was shot down over conflict-hit Ukraine.
Russia said the accusations against its military were "absolutely threadbare".
International arrest warrants have been issued for the four suspects and a court case will begin in the Netherlands on 9 March 2020.
The Dutch-led joint investigation team (JIT) named the men as Igor Girkin, Sergei Dubinsky and Oleg Pulatov from Russia, as well as Ukrainian Leonid Kharchenko.
The JIT, which is seeking to try the suspects under Dutch law, had previously said it had a "long list" of persons of interest and appealed again for witnesses as the investigation continued.
The most prominent of the four is Igor Girkin (also known as Strelkov), who prosecutors say is a former colonel in Russia's FSB intelligence service. He was given the minister of defence title in the rebel-held eastern Ukrainian city of Donetsk.
He is believed to be the highest military officer in the area who was in direct contact with the Russian Federation. In a statement Mr Girkin said: "I can only say that militia did not shoot down the Boeing."
The others charged are:
- Sergei Dubinsky (known as Khmury), who prosecutors say was employed by Russia's GRU military intelligence agency, was a deputy of Mr Girkin and in regular contact with Russia
- Oleg Pulatov, known as Giurza, who the JIT says was a former soldier of GRU special forces and deputy head of the intelligence service in Donetsk
- Ukrainian national Leonid Kharchenko, who has no military background but led a combat unit as a commander in eastern Ukraine, according to prosecutors
"These suspects are seen to have played an important role in the death of 298 innocent civilians", said Dutch chief prosecutor Fred Westerbeke.
"Although they did not push the button themselves, we suspect them of close co-operation to get the [missile launcher] where it was, with the aim to shoot down an aeroplane."
Investigators, he added, had "evidence showing that Russia provided the missile launcher".