The older brother of the Syrian boy whose dazed and bloodied face shocked people around the world, has died in Aleppo from wounds sustained in the same air strike.
Ali Daqneesh, 10, was wounded in Wednesday's air strike, the ABC was told.
He had internal bleeding and organ damage, doctors said.
His younger brother, five-year-old Omran Daqneesh, was pictured in the back of an ambulance after being pulled from the rubble, with an expression of incomprehension on his dust and blood-caked face.
The nurse who treated Omran has told the ABC the boy did not cry as he was being treated, describing him being "in shock".
"He didn't say anything except to ask for his parents," Abu Rajab from the Syrian American Medical Society said.
"They arrived shortly after, in a second wave of people.
"Only then once Omran saw them did he start crying."
Omran's parents told medical staff they would not speak for fear of reprisal from forces allied to the regime of President Bashar al Assad.
Situation in besieged areas 'nightmarish'
The video and pictures were widely circulated online and in the media, refocusing public opinion on Syria's five-year-old civil war and the plight of civilians, particularly in Aleppo.
Russian and Syrian warplanes have intensified their air strikes on the rebel-held east of the city since insurgents made an advance last month, breaking an effective siege.
Fighting and air strikes in and around Aleppo has killed 448 civilians so far this month, said the Syrian Observatory for Human Rights, a UK-based monitoring group.
Rebels, supported by the United States, Turkey and Gulf Arab nations, have been fighting since 2011 to oust Mr al-Assad, who is supported by Russia and Iran. Russia began air strikes last September.
On Friday, the World Food Programme described the situation in besieged areas as "nightmarish" amid growing international concern over the humanitarian cost of the war in Syria.
Russia said it supports the idea of weekly 48-hour ceasefires to allow humanitarian aid to enter besieged parts of Aleppo, a plan the rebels have also cautiously welcomed.
ABC/Reuters
